RRML - Recent developments in fatty acids profile determination in biological samples

RRML - Recent developments in fatty acids profile determination in biological samples - a review

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Nr. 23(4)/2015 DOI:10.1515/rrlm-2015-0035

Review

Recent developments in fatty acids profile determination in biological samples - a review

Ioana Tiuca, Katalin Nagy, Radu Oprean

Abstract:

The present paper is a literature review of the recent years dealing with the most important separation techniques of fatty acids in biological samples. Our aim was to make a synthesis of the analytical methods used, to note the most used ones, but also to mention other methods that are less utilized, which can have important advantages (such as less time consuming, greener reagents, etc.). Gas-chromatographic separation methods were described and compared to liquid chromatographic separations of fatty acids in different types of biological samples. In the same time, the importance of determining fatty acids profiles in biological samples was revealed, pointing out the possible implications in diagnostics of different types of disorders or remarking different profiles compared to healthy states.

Keywords: fatty acids, gas-chromatography, liquid-chromatography, biological samples

Received: 23.6.2015
Accepted: 13.9.2015
Published: 23.9.2015

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Tiuca I, Nagy K, Oprean R. Recent developments in fatty acids profile determination in biological samples - a review. Rev Romana Med Lab. 2015;23(4):371-84. DOI:10.1515/rrlm-2015-0035