RRML - Versant HCV Genotype 2.0 Assay (LiPA) in Hepatitis C Virus Genotype Determination

Main page
News
RJLabM Credits
Archive
- Current issue
- Ahead of print
- List of published issues
- 2025
  - Nr.1/2025
- 2024
  - Nr.4/2024
  - Nr.3/2024
  - Nr.2/2024
  - Nr.1/2024
  - Supplement 1/2024
- 2023
  - Nr.4/2023
  - Nr.3/2023
  - Nr.2/2023
  - Nr.1/2023
  - Supplement 1/2023
- 2022
  - Nr.4/2022
  - Nr.3/2022
  - Nr.2/2022
  - Nr.1/2022
  - Supplement 1/2022
- 2021
  - Nr.4/2021
  - Nr.3/2021
  - Nr.2/2021
  - Nr.1/2021
- 2020
  - Nr.4/2020
  - Nr.3/2020
  - Nr.2/2020
  - Nr.1/2020
  - Supplement 1/2020
- 2019
  - Nr.4/2019
  - Nr.3/2019
  - Nr.2/2019
  - Nr.1/2019
  - Supplement 1/2019
- 2018
  - Nr.4/2018
  - Nr.3/2018
  - Nr.2/2018
  - Nr.1/2018
  - Supplement 1/2018
  - Supplement 2/2018
  - Supplement 3/2018
- 2017
  - Nr.4/2017
  - Nr.3/2017
  - Nr.2/2017
  - Nr.1/2017
  - Supplement 1/2017
- 2016
  - Nr.4/2016
  - Nr.3/2016
  - Nr.2/2016
  - Nr.1/2016
  - Supplement 1/2016
- 2015
  - Nr.4/2015
  - Nr.3/2015
  - Nr.2/2015
  - Nr.1/2015
  - Supplement 1/2015
- 2014
  - Nr.4/2014
  - Nr.3/2014
  - Nr.2/2014
  - Nr.1/2014
  - Supplement 1/2014
- 2013
  - Nr.4/2013
  - Nr.3/2013
  - Nr.2/2013
  - Nr.1/2013
  - Supplement 1/2013
- 2012
  - Nr.4/2012
  - Nr.3/2012
  - Nr.2/2012
  - Nr.1/2012
  - Supplement 1/2012
- 2011
  - Nr.4/2011
  - Nr.3/2011
  - Nr.2/2011
  - Nr.1/2011
  - Supplement 1/2011
- 2010
  - Nr.4/2010
  - Nr.3/2010
  - Nr.2/2010
  - Nr.1/2010
  - Supplement 1/2010
- 2009
  - Nr.4/2009
  - Nr.3/2009
  - Nr.2/2009
  - Nr.1/2009
  - Supplement 1/2009
- 2008
  - Nr.4/2008
  - Nr.3/2008
  - Nr.2/2008
  - Nr.1/2008
  - Supplement 1/2008
- 2007
  - Nr.4/2007
  - Nr.3/2007
  - Nr.2/2007
  - Nr.1/2007
- 2006
  - Nr.4/2006
  - Nr.3/2006
  - Nr.2/2006
  - Nr.1/2006
- 2005
  - Nr.1/2005
Instructions for authors
Online applications
- Send an article
- Online payments
Editorial
About us
Links

ISSN online: 2284-5623

ISSN-L: 1841-6624

Rejection rate (2020): 75%

Journal Metrics

Impact Factor 0.5
Five Year Impact Factor 0.5
JCI 0.12

Top 10 downloaded articles - April 2025 -

Romanian Review of Laboratory ...	26
Association of neutrophil-to-l...	15
A comparative study of legisla...	11
Investigation of cytokine chan...	10
Implementing essential require...	8
Association of CD40 gene polym...	8
Understanding the key differen...	7
Small patients, big challenges...	7
Recomandările naționale ale ...	7
COVID-19 or systemic lupus ery...	7

Concept, Design & Programming
Dr. Adrian Man

Nr. 12(3)/2008

Versant HCV Genotype 2.0 Assay (LiPA) in Hepatitis C Virus Genotype Determination

Elena Luminiţa Enache, Liviu S. Enache

Abstract:

Hepatitis C virus (HCV) is a major cause of chronic liver disease, the prevalence of the infection being currently estimated at approximately 170 milion persons worldwide. HCV isolates have been classified into six main genotypes. Quick and accurate genotyping of HCV is becoming increasingly important for clinical management of chronic infection and as an epidemiological marker. Genotyping methods are frequently based on the analysis of the 5’ untranslated region (5’UTR) of HCV genome, which is not appropriate for the accurate discrimination of HCV strains at a subtype level. The newly developed Versant HCV Genotype 2.0 Assay (LiPA) uses sequence information from both the 5’UTR and the core region allowing the distinction between subtypes 1a and 1b inside genotype 1 and between genotype 1 and subtypes c to l of genotype 6. Hereby, we make a review of the literature evaluating this new genotyping assay.

Keywords: hepatitis C virus,genotyping,reverse hybridization,sequencing.

Download full text PDF
(242 KB)

Enache EL, Enache LS. Versant HCV Genotype 2.0 Assay (LiPA) in Hepatitis C Virus Genotype Determination. Rev Romana Med Lab. 2008;12(3):47-53