RRML - Clinical and paraclinical aspects in mental retardation and autism spectrum disorders

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Dr. Adrian Man

Nr. 16(3)/2009

Clinical and paraclinical aspects in mental retardation and autism spectrum disorders

Michaela Dobre, Paula Popa, Aurel Nechita, Lucian Puiu Georgescu

Abstract:

Mental retardation (RM) and autism spectrum disorders (ASD) are mental illnesses that severely impair individual development and have serious consequences that affect both family and community. The frequency of such illnesses is increasing, calling for a unitary collective effort towards diagnose and treatment. The study involved 62 patients diagnosed with RM and/or ASD, associated with anemia, hearing or sight impairments, epilepsy and also 14 cases of viral hepatitis type B. The study aimed to corroborate clinical information with paraclinical evidence in order to survey individual patient health evolution. Tests showed that patients with intellectual disabilities, whether receiving neuroleptic treatment or not, are frequently afflicted by anemia and water imbalances and very often exhibit metabolic acidosis. Such identified metabolic abnormalities should be justified by genetic and/or environmental factors. The complexity of autism spectrum disorders etiology invokes the multifactorial character of these diseases.

Keywords: mental retardation,autism,anemia,metabolic acidosis

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Dobre M, Popa P, Nechita A, Georgescu LP. Clinical and paraclinical aspects in mental retardation and autism spectrum disorders. Rev Romana Med Lab. 2009;16(3):59-69