RRML - The Use of Infrared Spectroscopy in the Investigation of Urolithiasis

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Nr. 18(4)/2010

The Use of Infrared Spectroscopy in the Investigation of Urolithiasis

Georgeta Sofia Popescu (Pintilie), I. Ionescu., Rodica Grecu, Anişoara Preda

Abstract:

Infrared (IR) spectroscopy is a modern physical-chemical method suitable for the investigation of kidney stones composition. The application of this method in our work was anticipated by performing the standard infrared-spectra on pure compounds: oxalic acid, oxalates, phosphate, carbonate, uric acid, and xanthine. This work reveals aspects regarding urolithiasis types by Fourier Transform Infrared (FTIR) Spectroscopy method. The purpose of this paper is to contribute to the determination of the urolithiasis composition correctly correlated with specific pathophysiological conditions. These results permit further investigation on the uroconcrements for which we have established the urolithiasis type and enable us to determine their metal concentration by atomic absorption spectroscopy. The data regarding the urolithiasis composition are important for clinical guidelines in the prophylaxis and methaphylaxis of urolithiasis.

Keywords: urinary calculi,FT-IR spectroscopy,qualitative composition,etiology

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Popescu (Pintilie) GS, Ionescu. I, Grecu R, Preda A. The Use of Infrared Spectroscopy in the Investigation of Urolithiasis. Rev Romana Med Lab. 2010;18(4):67-77