RRML - Predictive Value of Neutrophil Count for Postoperative Complications in Children after Surgery of Perforated Appendicitis
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Nr. 29(1)/2021 DOI:10.2478/rrlm-2021-0008
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Predictive Value of Neutrophil Count for Postoperative Complications in Children after Surgery of Perforated Appendicitis

Vesna Marjanovic, Ivana Budic, Ljubinka Jankovic-Velickovic, Marija Stevic, Milos Kostic, Dusica Simic

Correspondence should be addressed to: Vesna Marjanovic

Abstract:

Introduction: Perforated appendicitis (PA) in children is associated with a considerable risk for postoperative complications (POCs) such as wound infection and intra-abdominal abscess. The aim of this study was to determine the diagnostic accuracy of hematological parameters in the early POC detection in children after PA surgery. Materials and Methods: The study enrolled 71 patients with PA divided into two groups: 14 patients with POC (POC+ group) and 57 patients without POC (POC- group). Clinical and hematological parameters were followed preoperatively, prior to the surgery (PRO) and postoperatively on day 2 (POD2) and day 4 (POD4). Results: The POC+ group had longer duration of higher axillar temperature as well as extended intensive and inpatient care. This group also had a significantly lower absolute neutrophil count ratio between POD2 and POD4. According to the receiver operating characteristic curve analysis, relative neutrophil count on POD4 higher than 71.8% and the ratio of absolute neutrophil count between POD2 and POD4 lower than 44.5% were found to be useful for predicting POC. Conclusion: Absolute neutrophil count ratio between POD2 and POD4 and relative neutrophil count at POD4 could be efficient in identifying children at higher risk of developing POC after PA surgery.

Keywords: perforated appendicitis, predictors of postoperative complication, children

Received: 22.10.2020
Accepted: 29.12.2020
Published: 14.1.2021

 
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How to cite
Marjanovic V, Budic I, Jankovic-Velickovic L, Stevic M, Kostic M, Simic D. Predictive Value of Neutrophil Count for Postoperative Complications in Children after Surgery of Perforated Appendicitis. Rev Romana Med Lab. 2021;29(1):77-84. DOI:10.2478/rrlm-2021-0008